A article published in Current Atherosclerosis Reports indicated that the original findings of the WHI showed no association between the two supplements and stroke risk.
And a article published in the Journal of the American Heart Association actually found that calcium supplements increase the risk of stroke, but combining them with vitamin D seemed to offset this result. The takeaway? Have a conversation with your doctor about the risks associated with taking these two supplements together, to ensure the benefits outweigh the risks.
Taking a multivitamin that includes niacin, or vitamin B3, is typically safe in combination with other nutrients. However, if you take niacin supplements and medications to help control your cholesterol — specifically, simvastatin — there are a few combinations that you should avoid.
According to the MedlinePlus , which is powered by the U. National Library of Medicine, when you're taking a combination of niacin and simvastatin, supplementing with vitamins C and E or beta carotene could interfere with this duo's ability to raise your HDL good cholesterol. A caveat: This interaction has only been studied in those who currently have coronary artery disease CAD.
It is not known if this interaction holds true if you do not have CAD. Vitamin B12 and folate are both commonly prescribed supplements, with the latter being especially important during pregnancy. Older adults, those following a vegan diet and individuals with gastrointestinal disorders are encouraged to take a B12 supplement. While taking folate and vitamin B12 at the same time is not problematic in general, higher folate levels can mask a B12 deficiency. The problem? Low levels of vitamin B12 can lead to megaloblastic anemia, a condition in which the red blood cells are unusually large, but decreased in number.
Taking large amounts of folate can correct the anemia, making you think that you are good to go. However, if the underlying B12 deficiency is not addressed and corrected, permanent nerve damage can result, according to the National Institutes of Health NIH.
If you are at risk for a B12 deficiency, seek your doctor's advice regarding proper supplementation. And keep in mind that you should never consume more than 1, micrograms of folic acid from fortified foods or supplements unless directed by your doctor. Vitamin K plays a critical role in your body's ability to properly clot your blood. If your doctor recommends a vitamin K supplement, avoid taking high dosages of vitamin E, which may counteract the effects of vitamin K, according to MedlinePlus.
Learn more about the different names and types of vitamin E, including d-alpha tocopheryl succinate, natural and synthetic. If you have osteoporosis, you may be interested in supplements for bone health. Find out which supplements can increase bone strength and density. Should you be taking calcium and magnesium together? Find out how to ensure optimal absorption of both calcium and magnesium by following these guidelines.
Learn more about fully reduced vitamin C, including tips on how best to store vitamin C supplements. Learn more about the benefits of getting vitamins from food versus supplements, natural versus synthetic vitamins, and more. Find out which supplements may help reduce flatulence gas , and learn which supplements or foods may worsen symptoms of flatulence. Vitamin B says to take with a meal. Does it matter if it is at breakfast instead of lunch or dinner? It should not matter which meal.
It is not fat soluble, so you don't need to take it with a meal high in fats, as with fat soluble vitamins. Reply to this post…. When it is recommended to take certain vitamins together, such as Vitamin D and Magnesium, does that mean at the same time or just on the same day? Hi Karen - Adequate intake of magnesium helps maintain optimal levels of vitamin D, as discussed in our Vitamin D Review.
However this does not mean that the two need to be take together, or even that you need to supplement with either if you already get enough of them from your diet and, for vitamin D, sun exposure. I understand but that doesn't answer my question. I don't know what "take together" means. Pretend I need to take 2 supplements and it is recommended to take them together. Does that mean at the same time or the same day? Karen - It will depend on which supplements are to be taken.
In this case, they would not have to be taken at the same time. In fact, you should take vitamin D with or shortly before a meal containing fats, while magnesium does not have to be taken with a meal. Hi Ellen - Yes, this applies to plant-based calcium supplements as well. Suggesting people take Vitamin D in the evening with dinner for increased absorption is not good, it blocks melatonin production. Best to take Vitamin D with a high fat breakfast, which we should all have to lower blood sugar and insulin.
I know you don't say take it with dinner, but you elude to a study where it was absorbed better at dinner, but that is NOT the best time to take it. Hi Eileen - It's true that high doses vitamin D may decrease the production of melatonin. I am 63 and having sleeping problems. I had been taking per day to up my levels but I suspect the D was the culprit so I have stopped taking it for awhile. Fish oil is a commonly used supplement.
Should I still try to have some fat in the meal before taking these? Your site should never use the term, "Vitamin K". Hi David - Although our report is entitled Vitamin K Supplements, it provides extensive information about the differences between vitamins K1 and K2 and the many forms of K2, e. Vitamin D doses also pause the production of melatonin, so I would advise having your Vitamin D in an earlier meal than dinner if you have problems with insomnia.
Thank you Eileen. I am a little confused about calcium and magnesium. I have always operated under the assumption that they are best taken together, along with vitamin D, as each of these aids in the absorption of the others. Is this incorrect? Thank you for your question. You might be prescribed higher amounts of zinc following surgery, but that should generally be only about 2 weeks.
So rather than adding a copper supplement, discontinue the zinc supplement or check with your doctor about the dose and duration. You are correct, Jeannemarie. For your privacy, only your first name from your account followed by a random number will appear with your comment.
Your last name and email address will not be displayed. All rights reserved. This site is intended for informational purposes only and not to provide medical advice. Learn how to enable it here. About ConsumerLab.
Contact Us Privacy Policy. Save to favorites This feature is restricted to active members. Join now to save favorites and get all member benefits, including over 1, reviews. Join Now Already a member? Our Members Asked: Which vitamins and minerals should be taken together or separately?
Recent CL Answers Which deodorants and antiperspirants are contaminated with benzene and which are not? Which ingredients should toothpaste contain, and which should be avoided? Flu Vaccines: How do different flu vaccines compare and which is best for older people? Magnesium is important for the body to make vitamin D3 absorbable, and enzymes in the liver and kidneys require magnesium to break down vitamin D3.
Vitamin D3 boosts the immune system, regulates blood pressure and strengthens bones, teeth and muscles. Magnesium, on the other hand, will help strengthen bones, relieving muscle tension and muscle spasms. These two nutrients can help you deal with heart conditions, as well as to keep cholesterol levels in check. Omega-3 and vitamin E are two critical nutrients that provide various benefits for people dealing with coronary artery disease CAD.
In fact, as per a study published by the US National Library of Medicine, co-administration of omega 3 and vitamin E can beneficially decrease serum insulin and insulin resistance in CAD patients. Moreover, a combination of these two supplements can significantly reduce VLDL very-low-density lipoprotein levels for people dealing with cholesterol issues.
Overall, stress levels can also be lowered using these supplements as Omega-3 improves psychological health. When taken in combination, magnesium and zinc have mutual benefits. Magnesium helps the body regulate its zinc levels, while zinc ensures that magnesium is absorbed effectively by the body.
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